Astera

Principal AI Scientist (Polytope Bio)

Who can apply: US-based role. The employer has not said which states are eligible — confirm before applying.
Location as listed by the employer: “Remote”
Apply on Astera's site ↗

Opens the employer's official application page.

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About this role

Astera is hiring for a Principal AI Scientist (Polytope Bio) role (full-time). See the official posting for full details.

Requirements

  • Research Experience: PhD in machine learning, computational biology, or a related field with a minimum of 2 to 5 years of industry research experience post-PhD (accomplished researchers without a PhD are also encouraged…
  • Model Training: You have trained models from scratch, not just fine-tuned or called APIs. You have owned real training runs, know where they break, and know how to debug them.
  • Modern Algorithms: Hands-on experience with generative diffusion models and/or transformer architectures.
  • Reinforcement Learning: Deep familiarity with modern reinforcement learning and preference-optimization methods for deep learning.
  • Builder mindset: A track record of strong research via publications, open-source work, shipped models, or equivalent evidence that you drive results. You are highly self-directed but thrive in a tight-knit, collaborativ…
  • Entrepreneurial spirit: Comfort operating with ambiguity and research ownership. You are excited to build the infrastructure and grow the team.

Summarized from the employer's posting — check the full posting for every requirement.